Notorious criminal Frank Griffin and his gang of outlaws are on a mission -- get revenge on Roy Goode, a former protege who betrayed the brotherhood. On the run, Roy seeks refuge in isolated mining town La Belle, N.M., where he lives with Alice Fletcher, a hardened widow and outcast. When word reaches La Belle, which is governed mainly by women, that Griffin is headed there, the residents of the town band together to defend against his murderous gang.